Question

An HIV positive patient with a CD4 COUNT OF 300/Cumm presents with mucosal lesions in the mouth as shown in the figure. On microscopy budding yeasts and pseudohyphae are seen. A most probable diagnosis is ?

• A. Candidiasis
• B. Hairy leukoplakia
• C. Lichen planus
• D. Diphtheria

Answer 1

The Correct Option is A

An HIV positive patient with a CD4 count of 300/Cumm is immunosuppressed, making them more susceptible to opportunistic infections. The presence of mucosal lesions in the mouth combined with the microscopy findings of budding yeasts and pseudohyphae strongly indicates an infection caused by a fungal organism.

The most common fungal infection in this scenario is caused by Candida species, which are responsible for oral candidiasis (also known as thrush). The description of "budding yeasts and pseudohyphae" is characteristic of Candida under a microscope.

Thus, the most probable diagnosis for the lesions described is:

Candidiasis