Step 1: Alopecia areata presents as sudden, well-defined, round or oval patches of non-scarring hair loss, often with exclamation mark hairs at the margins.
Step 2: It is an organ-specific autoimmune disorder. T lymphocytes attack the anagen hair follicles after a loss of their normal immune privilege, halting hair growth in the affected areas.
Step 3: It is associated with other autoimmune conditions such as thyroid disease, vitiligo and pernicious anemia, supporting its autoimmune basis. The hair loss is reversible because the follicles are not destroyed.
Step 4: It is not an allergic, anaphylactic or bacterial process. Therefore alopecia areata is an autoimmune disorder.