Question:
All of the following statements about pseudohypoparathyroidism are true, except:
All of the following statements about pseudohypoparathyroidism are true, except:
Show Hint
In pseudohypoparathyroidism PTH is high because tissues resist it.
Updated On: Jun 24, 2026
- Decreased serum PTH
- Decreased serum calcium
- Increased serum phosphate
- Albright hereditary osteodystrophy
Show Solution
Verified By Collegedunia
The Correct Option is A
Solution and Explanation
Step 1: Pseudohypoparathyroidism means the body looks like it lacks PTH effect, but the gland is fine. The defect is end-organ resistance to PTH, classically from a G protein (GNAS) defect in the receptor pathway.
Step 2: Because target tissues cannot respond to PTH, calcium stays low and phosphate stays high, just like true hypoparathyroidism. So decreased serum calcium (B) and increased serum phosphate (C) are both true.
Step 3: The key difference from true hypoparathyroidism is the PTH level. Since the resistance keeps calcium low, the parathyroid glands are continuously stimulated and pump out more hormone. So serum PTH is increased, not decreased. Option A is therefore the false statement.
Step 4: Type 1a pseudohypoparathyroidism shows the physical features of Albright hereditary osteodystrophy: short stature, round face, short fourth and fifth metacarpals, and obesity. So option D is true.
Step 5: The untrue statement is decreased serum PTH; it is actually high.
Correct option: A.
Step 2: Because target tissues cannot respond to PTH, calcium stays low and phosphate stays high, just like true hypoparathyroidism. So decreased serum calcium (B) and increased serum phosphate (C) are both true.
Step 3: The key difference from true hypoparathyroidism is the PTH level. Since the resistance keeps calcium low, the parathyroid glands are continuously stimulated and pump out more hormone. So serum PTH is increased, not decreased. Option A is therefore the false statement.
Step 4: Type 1a pseudohypoparathyroidism shows the physical features of Albright hereditary osteodystrophy: short stature, round face, short fourth and fifth metacarpals, and obesity. So option D is true.
Step 5: The untrue statement is decreased serum PTH; it is actually high.
Correct option: A.
Was this answer helpful?
0
0
Top NEET PG Medicine Questions
- Identify the condition associated with the murmur in the image below
- A young man came to the medical OPD with complaints of early morning backache and stiffness, which improves on exercise, and persistent red eyes. On examination, lung expansion was less than 3 cm. X-ray is shown in the image given below.
What is the most probable diagnosis? - A patient with hyperkalemia and elevated urea levels underwent dialysis. Towards the end of the session, she became drowsy and had a sudden seizure episode. On examination, thepatient was hypotensive. What is the treatment for this condition?
- A female patient presents to the emergency department with severe restlessness, palpitations, and tremors. She is a known case of bronchial asthma. On examination, the neck looksswollen. Blood pressure is elevated, and tachycardia is noted. ECG shows atrial fibrillation.Which of the following drugs is used for immediate management in this patient?
- A 30-year-old male is found to be positive for HBsAg and HBeAg and is diagnosed with chronic hepatitis B. The patient’s viral load was 2x 100000 and SGPT is found to be doubled. What is the appropriate management in this patient? SGPT-Serum glutamate pyruvate transaminase
View More Questions
Top NEET PG Hyperthyroidism Questions
- A patient has fatigue but is not gaining weight, and the body feels warm. Investigations are most likely to show:
- A patient presents with a high TSH and a low T4. What is the probable diagnosis?
- A 15 day old baby came with a history of seizures. Blood tests revealed Ca 5 mg/dl, PO4 9 mg/dl, PTH 30 pg/ml (normal 10 to 60). What is the most probable diagnosis?
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions