Question:
All of the following decrease bone resorption in osteoporosis except?
All of the following decrease bone resorption in osteoporosis except?
Show Hint
One of these builds bone (anabolic PTH) rather than blocking osteoclasts.
Updated On: Jun 24, 2026
- Alendronate
- Etidronate
- Strontium
- Teriparatide
Show Solution
Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: Osteoporosis drugs fall into two groups: ANTIRESORPTIVE agents (which inhibit osteoclasts and reduce bone breakdown) and ANABOLIC agents (which stimulate osteoblasts and build new bone). The question asks for the one that does NOT decrease bone resorption.
Step 2: Alendronate and Etidronate are bisphosphonates. They concentrate in bone and inhibit osteoclast-mediated resorption, so both are antiresorptive.
Step 3: Strontium ranelate has a dual action but is classically grouped with antiresorptive agents because it reduces osteoclastic bone resorption (while also mildly promoting formation).
Step 4: Teriparatide is recombinant parathyroid hormone (PTH 1-34). Given as intermittent daily injections, it is an ANABOLIC drug that stimulates osteoblasts and increases bone FORMATION rather than decreasing resorption. Hence it is the exception.
Conclusion: The correct answer is Teriparatide, matching the printed key.
Step 2: Alendronate and Etidronate are bisphosphonates. They concentrate in bone and inhibit osteoclast-mediated resorption, so both are antiresorptive.
Step 3: Strontium ranelate has a dual action but is classically grouped with antiresorptive agents because it reduces osteoclastic bone resorption (while also mildly promoting formation).
Step 4: Teriparatide is recombinant parathyroid hormone (PTH 1-34). Given as intermittent daily injections, it is an ANABOLIC drug that stimulates osteoblasts and increases bone FORMATION rather than decreasing resorption. Hence it is the exception.
Conclusion: The correct answer is Teriparatide, matching the printed key.
Was this answer helpful?
0
0
Top NEET PG Pharmacology Questions
- A bronchial asthma patient on inhalational steroids presented with white patchy lesions on the tongue and buccal mucosa. What is the drug that can be used to treat this condition?
- A pregnant woman with a history of bronchial asthma is in the third stage of labor. Which drugs should be avoided in managing postpartum hemorrhage in this mother?
- Name the drug that acts on both the marked areas.
- A patient with a previous history of myocardial infarction and ventricular arrhythmia is ontreatment for a few months. He developed fatigue, dyspnea, and weight gain. He had also developed pulmonary fibrosis. Which of the following drugs is responsible for the side effects mentioned above?
- A young female comes to the emergency department after consuming 100 aspirin tablets.What should be the next step in management?
View More Questions
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions