Question

All of the following are the components of MEN-2b except:

• A. Megalocon
• B. Marfanoid habitus
• C. Mucosal neuroma
• D. Parathyroid adenoma

Hint:

In MEN-2b, early detection of pheochromocytomas and medullary thyroid cancer is essential for management.

Answer 1

The Correct Option is D

The question asks about the components of Multiple Endocrine Neoplasia type 2b (MEN-2b), with the exception of one incorrect option.

MEN-2b is a part of the Multiple Endocrine Neoplasia syndromes, which are hereditary conditions associated with tumors of endocrine glands. MEN-2b is characterized by a specific set of clinical features:

• Megalocon: This refers to an abnormally large colon, which is considered a component in some cases of MEN-2b due to associated gastrointestinal issues.
• Marfanoid habitus: Individuals with MEN-2b often exhibit features resembling Marfan syndrome, known as marfanoid habitus, with long limbs and fingers.
• Mucosal neuroma: This is a common feature of MEN-2b, where benign tumors develop in mucosal tissues, particularly around the oral cavity.
• Parathyroid adenoma: This is not a feature of MEN-2b. Parathyroid adenomas are more often associated with MEN-1 and MEN-2a syndromes, not MEN-2b.

Therefore, the component that is not typically associated with MEN-2b is Parathyroid adenoma.

Thus, the correct answer is: Parathyroid adenoma.