Question

A researcher wants to know whether there is an association of CRP values with risk of MI/Cancer. They started to take CRP readings. 4 Values of RR was plotted (0.5, 1.5,1.7,1.8) with respect to CRP

• A. CRP increase disease/cancer risk
• B. CRP has no relationship
• C. CRP decreases & disease decreases
• D. No association in first interval

Answer 1

The Correct Option is A

To determine the association between CRP (C-reactive protein) values and the risk of MI (myocardial infarction) or cancer, we assess the provided relative risk (RR) values: 0.5, 1.5, 1.7, and 1.8. The relative risk describes the likelihood of a disease occurring in the group of interest (high CRP levels) compared to a baseline group. If RR > 1, there is an increased risk of disease with higher CRP values; if RR = 1, there is no association; if RR < 1, there is a decreased risk.

Let's analyze the given RR values: 

• RR = 0.5: Indicates a decreased risk of disease, as CRP levels increase.
• RR = 1.5: Indicates a 50% increased risk of disease, as CRP levels increase.
• RR = 1.7: Indicates a 70% increased risk of disease, as CRP levels increase.
• RR = 1.8: Indicates an 80% increased risk of disease, as CRP levels increase.

From these values, we can deduce that when CRP values increase, the relative risk for disease (MI or cancer) also increases, except in the first interval where CRP seemed to decrease the risk. However, the trend from 1.5 to 1.8 suggests a strong association between increased CRP levels and increased risk for disease, which aligns with the correct answer: CRP increase disease/cancer risk.