Question:
A patient with a malignancy is undergoing chemotherapy. The platelet counts were reduced after the previous cycle of chemotherapy. Which of the following drugs can be used to treat this patient?
A patient with a malignancy is undergoing chemotherapy. The platelet counts were reduced after the previous cycle of chemotherapy. Which of the following drugs can be used to treat this patient?
Updated On: Jun 18, 2025
- Oprelvekin (IL-11
- Filgrastim
- Erythropoietin
- Amifostine
Show Solution
Verified By Collegedunia
The Correct Option is A
Solution and Explanation
A patient undergoing chemotherapy is experiencing reduced platelet counts due to the treatment. This condition is known as thrombocytopenia, which is a common side effect of chemotherapy because it can damage the bone marrow where blood cells are produced.
The drugs listed in the options have different roles:
- Oprelvekin (IL-11): This drug is specifically used to increase platelet counts. Oprelvekin is a recombinant form of Interleukin-11 (IL-11), a cytokine that stimulates the proliferation of megakaryocyte progenitor cells and increases platelet production in the bone marrow, making it suitable for treating chemotherapy-induced thrombocytopenia.
- Filgrastim: This drug is a granulocyte colony-stimulating factor (G-CSF) that stimulates the bone marrow to produce white blood cells, mainly used for treating neutropenia.
- Erythropoietin: This hormone stimulates the production of red blood cells, helpful in treating anemia.
- Amifostine: A cytoprotective agent used to reduce the side effects of chemotherapy and radiation therapy, but it does not specifically increase platelet counts.
Given these roles, Oprelvekin (IL-11) is the most suitable choice for treating reduced platelet counts in this patient undergoing chemotherapy.
Was this answer helpful?
0
0
Top NEET PG Pharmacology Questions
- A bronchial asthma patient on inhalational steroids presented with white patchy lesions on the tongue and buccal mucosa. What is the drug that can be used to treat this condition?
- A pregnant woman with a history of bronchial asthma is in the third stage of labor. Which drugs should be avoided in managing postpartum hemorrhage in this mother?
- Name the drug that acts on both the marked areas.
- A patient with a previous history of myocardial infarction and ventricular arrhythmia is ontreatment for a few months. He developed fatigue, dyspnea, and weight gain. He had also developed pulmonary fibrosis. Which of the following drugs is responsible for the side effects mentioned above?
- A young female comes to the emergency department after consuming 100 aspirin tablets.What should be the next step in management?
View More Questions
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions