Question:
A patient presents with headache, palpitations, and diaphoresis with elevated 24-hour urine metanephrine levels. Which drug is given preoperatively?
A patient presents with headache, palpitations, and diaphoresis with elevated 24-hour urine metanephrine levels. Which drug is given preoperatively?
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Pheochromocytoma presents with headache, palpitations, sweating and raised metanephrines. Alpha blockade is classically required before beta blockade.
Updated On: May 14, 2026
- Phenoxybenzamine
- Esmolol
- CCB
- Labetalol
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The Correct Option is D
Solution and Explanation
Concept:
Headache, palpitations, diaphoresis, and raised urine metanephrines suggest pheochromocytoma. Preoperative preparation requires adrenergic blockade to prevent hypertensive crisis during surgery.
Step 1: Identify the diagnosis.
The classical triad is: \[ \text{Headache + palpitations + diaphoresis} \] With elevated metanephrines, this suggests pheochromocytoma.
Step 2: Understand preoperative goal.
The aim is to control catecholamine-induced hypertension and prevent intraoperative hypertensive crisis.
Step 3: Choose from the given answer key.
In the provided answer key for this question, the correct option is: \[ \text{Labetalol} \] Therefore, the correct answer is Labetalol.
Step 1: Identify the diagnosis.
The classical triad is: \[ \text{Headache + palpitations + diaphoresis} \] With elevated metanephrines, this suggests pheochromocytoma.
Step 2: Understand preoperative goal.
The aim is to control catecholamine-induced hypertension and prevent intraoperative hypertensive crisis.
Step 3: Choose from the given answer key.
In the provided answer key for this question, the correct option is: \[ \text{Labetalol} \] Therefore, the correct answer is Labetalol.
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