Question

A patient presents to you with multiple anogenital warts. The biopsy of these lesions showed squamous atypia. Which of the following human papillomavirus types are considered high-risk?

• A. HPV 2
• B. HPV 18
• C. HPV 6
• D. HPV 11

Answer 1

The Correct Option is B

The presence of squamous atypia in the biopsy of anogenital warts suggests a potential risk for progression to malignancy. Certain types of human papillomavirus (HPV) are known to be associated with a higher risk of cancer development, especially cervical cancer, among others. These are referred to as high-risk HPV types.

The high-risk HPV types include HPV 16 and HPV 18, among others. In this context, the primary focus is on HPV 18, which is one of the high-risk types associated with squamous atypia and is known to contribute significantly to the development of cervical cancer.

Among the given options, HPV types 6 and 11 are typically associated with benign lesions such as anogenital warts and are considered low-risk. Similarly, HPV type 2 is also not classified as high-risk. Therefore, the correct high-risk HPV type from the given options, which is associated with squamous atypia, is HPV 18.