Question

A female with hirsutism, amenorrhoea and obesity. Diagnosis?

• A. PCOD
• B. Ovarian tumor
• C. Androgen insensitivity syndrome
• D. Turner syndrome

Hint:

A common reproductive age triad of excess hair, irregular periods and weight gain.

Answer 1

The Correct Option is A

Step 1: The triad of hirsutism (excess male pattern hair), oligo or amenorrhoea (menstrual irregularity) and obesity in a reproductive age woman is the classic picture of polycystic ovarian disease or syndrome.

Step 2: PCOD reflects hyperandrogenism plus chronic anovulation, often with insulin resistance, producing exactly these clinical and biochemical features, so option (a) is correct.

Step 3: An androgen secreting ovarian tumour (b) would cause rapidly progressive virilisation with markedly high testosterone and is far less common than PCOD for this slow indolent presentation.

Step 4: Androgen insensitivity syndrome (c) occurs in a genetically male individual who is phenotypically female with absent body hair, the opposite of hirsutism, while Turner syndrome (d) features short stature and primary amenorrhoea from gonadal dysgenesis without hyperandrogenism.