Hemophilia is a genetic disorder that affects blood clotting. It is an X-linked recessive condition, meaning that it is carried on the X chromosome. Males are more commonly affected because they have only one X chromosome. Hemophilia results from deficiencies in clotting factors such as factor VIII (Hemophilia A) or factor IX (Hemophilia B), leading to prolonged bleeding.
| List I (Enzyme) | List II (Function) |
|---|---|
| (A) Cytochrome oxidase | (I) Electron transport system |
| (B) Topoisomerases | (II) Change linking number |
| (C) Cohesins | (III) DNA Replication |
| (D) PCNA | (IV) Cell cycle |