Concept:
Chronic venous insufficiency causes venous hypertension in the lower limbs. It can lead to edema, pigmentation, venous eczema, lipodermatosclerosis, and venous ulcers.
Step 1: Identify the condition.
The question describes chronic venous changes in the lower limb.
Step 2: Recall complications.
Chronic venous insufficiency may cause:
\[
\text{Venous eczema + pigmentation + lipodermatosclerosis + venous ulcer}
\]
Step 3: Select the true statement.
The true statement is:
\[
\text{Eczema or lipodermatosclerosis may develop}
\]
Therefore, the correct answer is Eczema or lipodermatosclerosis may develop.