Question:

A 55-year-old male presents with pain and swelling in the lower jaw. On clinical examination, tenderness is noted over the left angle and body of the mandible, along with mild bucco-lingual cortical expansion. An orthopantomogram (OPG) reveals the radiographic findings shown. What is the most likely diagnosis?
7

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Odontogenic keratocyst commonly occurs in posterior mandibleShows well-defined radiolucency with minimal bucco-lingual expansion.
Updated On: Feb 17, 2026
  • Ossifying fibroma
  • Ameloblastoma
  • Osteoblastoma
  • Odontogenic keratocyst
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The Correct Option is D

Solution and Explanation

Step 1: Analyze the clinical presentation.
The patient is middle-aged with pain and swelling in the mandibular angle and body regionThere is mild bucco-lingual expansionOdontogenic keratocysts commonly occur in the posterior mandible
Step 2: Interpret radiographic features.
The OPG shows a well-defined radiolucent lesion in the posterior mandibleOdontogenic keratocysts typically present as well-corticated radiolucenciesThey may grow extensively in the anteroposterior direction with minimal cortical expansion
Step 3: Evaluate the options.
(A) Ossifying fibroma: Usually presents as a mixed radiolucent-radiopaque lesion with significant expansion
(B) Ameloblastoma: Often shows multilocular "soap-bubble" or "honeycomb" appearance with marked expansion
(C) Osteoblastoma: Typically produces radiopaque or mixed lesions and is less common in this location
(D) Odontogenic keratocyst: Appears as a well-defined radiolucent lesion in posterior mandible with minimal expansionMatches the described features
Step 4: Conclusion.
Based on posterior mandibular location, well-defined radiolucency, and mild expansion, the most likely diagnosis is odontogenic keratocyst
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