Question:

A 46-year-old woman presents with heavy menstrual bleeding. USG shows endometrial thickness of 16 mm. What is the next best step?

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Perimenopausal abnormal uterine bleeding with thickened endometrium = endometrial biopsy.
Updated On: Aug 27, 2026
  • Hysterectomy
  • Endometrial biopsy
  • HPV testing
  • Progesterone therapy
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The Correct Option is B

Solution and Explanation

Concept: Abnormal uterine bleeding in a perimenopausal woman with increased endometrial thickness should be evaluated by endometrial biopsy to rule out hyperplasia or malignancy.

Step 1:
Identify the age group.
A 46-year-old woman is in the perimenopausal age group, where abnormal bleeding must be evaluated carefully.

Step 2:
Interpret endometrial thickness.
Endometrial thickness of: \[ 16 \text{ mm} \] is increased and needs tissue diagnosis.

Step 3:
Choose the next best step.
Before giving hormonal therapy or doing hysterectomy, diagnosis should be confirmed by: \[ \text{Endometrial biopsy} \] Therefore, the correct answer is Endometrial biopsy.
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