Question:
Which products of cell wear and tear get accumulated in lysosomes with age in the cell body of neuron?
Which products of cell wear and tear get accumulated in lysosomes with age in the cell body of neuron?
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Lipofuscin = aging pigment in neurons.
Updated On: Jun 20, 2026
- Lipofuscin granules
- Histamine
- Bradykinin
- Hemozoin
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The Correct Option is A
Solution and Explanation
Step 1: Understanding lysosomal function.
Lysosomes digest cellular waste and damaged organelles over time.
Step 2: Age-related accumulation.
In long-lived cells like neurons, incomplete digestion leads to pigment accumulation.
Step 3: Lipofuscin formation.
Lipofuscin is called “wear and tear pigment” formed due to oxidation and incomplete lysosomal degradation.
Step 4: Evaluating other options.
- Histamine: signaling molecule.
- Bradykinin: inflammatory peptide.
- Hemozoin: malaria pigment.
Step 5: Biological reasoning.
Neurons are long-lived, so lipofuscin accumulates over time.
Step 6: Final conclusion.
Therefore, correct answer is lipofuscin granules.
Lysosomes digest cellular waste and damaged organelles over time.
Step 2: Age-related accumulation.
In long-lived cells like neurons, incomplete digestion leads to pigment accumulation.
Step 3: Lipofuscin formation.
Lipofuscin is called “wear and tear pigment” formed due to oxidation and incomplete lysosomal degradation.
Step 4: Evaluating other options.
- Histamine: signaling molecule.
- Bradykinin: inflammatory peptide.
- Hemozoin: malaria pigment.
Step 5: Biological reasoning.
Neurons are long-lived, so lipofuscin accumulates over time.
Step 6: Final conclusion.
Therefore, correct answer is lipofuscin granules.
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