Question:

Which of the following histones is NOT part of the nucleosome core?

Show Hint

Nucleosome core: H2A, H2B, H3, H4 (two copies each).
H1: linker histone, not part of core.
  • H1
  • H2
  • H3
  • H4
Show Solution
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The Correct Option is A

Solution and Explanation

Step 1: Understanding the Concept:
Nucleosomes are the structural units of chromatin.
They consist of DNA wrapped around histone proteins.

Step 2: Key Formula or Approach:

No specific formula.
Need to know the components of nucleosomes.

Step 3: Detailed Explanation:

The nucleosome core consists of two copies each of H2A, H2B, H3, and H4.
The H1 histone is a linker histone.
It binds to the DNA between nucleosomes.
Thus, H1 is NOT part of the nucleosome core.

Step 4: Final Answer:

H1 is NOT part of the nucleosome core.
Hence, the correct option is (A).
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