Question:

Which of the following drugs is used for narcoanalysis?

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The original truth serum is the antimuscarinic hyoscine.
Updated On: Jun 24, 2026
  • Atropine
  • Phenobarbitone
  • Scopolamine
  • Pethidine
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The Correct Option is C

Solution and Explanation

Step 1: Narcoanalysis (the so-called truth serum test) puts a person into a half-conscious, suggestible hypnotic state in which they are thought to speak more freely.
Step 2: The drugs classically used are the rapidly acting agents that produce this twilight sedation. These include scopolamine (hyoscine), and short-acting barbiturates such as thiopentone and sodium amytal.
Step 3: Among the given options, scopolamine is the recognised narcoanalysis agent. It was historically the original truth serum.
Step 4: Why the others are wrong. Atropine is an anticholinergic used for bradycardia and as an antidote, not for narcoanalysis. Phenobarbitone is a long-acting barbiturate used as an anticonvulsant, not the short-acting type used for the test. Pethidine is an opioid analgesic.
Step 5: The answer is option C, scopolamine.
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