Step 1: Recall what anaemia means.
Anaemia is a condition in which the blood has a lower than normal amount of healthy red blood cells or a reduced level of the protein that carries oxygen inside them. This leads to tiredness, weakness and pale skin because less oxygen reaches the body's tissues.
Step 2: Identify the substance that falls in anaemia.
The oxygen carrying protein present in red blood cells is called haemoglobin. In anaemia, either the number of red blood cells falls or the haemoglobin content inside them falls, so the overall haemoglobin level in the blood goes down. This is in fact how anaemia is diagnosed, by measuring haemoglobin levels in a blood test.
Step 3: Rule out the other options.
Riboflavin is Vitamin B2, a vitamin needed for energy production in cells, and it is not the marker used to define anaemia. Myoglobin is a protein found in muscle tissue, not blood, and it stores oxygen for the muscles rather than carrying it through the bloodstream. Carotene is a plant pigment that the body converts into Vitamin A, and it has no direct role in defining anaemia.
Final Answer:
Haemoglobin decreases in anaemia.
\[ \boxed{\text{Haemoglobin}} \]