Question:
Which of the following anthelmintics belongs to the group- Imidazothiazoles?
Which of the following anthelmintics belongs to the group- Imidazothiazoles?
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Remember the classic members of the Imidazothiazole anthelmintic family: Tetramisole and Levamisole.
These agents act as nicotinic acetylcholine receptor agonists, inducing paralysis in nematode parasites.
These agents act as nicotinic acetylcholine receptor agonists, inducing paralysis in nematode parasites.
Updated On: Aug 24, 2026
- Nitroxynil
- Haloxon
- Thiabendazole
- Tetramisole
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
Anthelmintics are classified into different chemical classes based on their molecular structures and modes of action.
Imidazothiazoles are a major group of broad-spectrum nematocides that act as cholinergic agonists, causing spastic paralysis in susceptible worms.
Step 2: Detailed Explanation:
Let us review the chemical classes of the listed anthelmintic compounds:
- Nitroxynil: Belongs to the halogenated nitrophenolic compound class, primarily used as a flukicide (fasciolicide) by uncoupling oxidative phosphorylation.
- Haloxon: An organophosphate compound that acts by inhibiting acetylcholinesterase enzymes in parasites.
- Thiabendazole: The prototype member of the benzimidazole chemical group, which inhibits microtubule polymerization by binding to beta-tubulin.
- Tetramisole: Along with its active L-isomer levamisole, tetramisole is the classic representative of the imidazothiazole chemical class.
Step 3: Final Answer:
Therefore, Tetramisole is the compound belonging to the Imidazothiazole group, making (D) the correct option.
Anthelmintics are classified into different chemical classes based on their molecular structures and modes of action.
Imidazothiazoles are a major group of broad-spectrum nematocides that act as cholinergic agonists, causing spastic paralysis in susceptible worms.
Step 2: Detailed Explanation:
Let us review the chemical classes of the listed anthelmintic compounds:
- Nitroxynil: Belongs to the halogenated nitrophenolic compound class, primarily used as a flukicide (fasciolicide) by uncoupling oxidative phosphorylation.
- Haloxon: An organophosphate compound that acts by inhibiting acetylcholinesterase enzymes in parasites.
- Thiabendazole: The prototype member of the benzimidazole chemical group, which inhibits microtubule polymerization by binding to beta-tubulin.
- Tetramisole: Along with its active L-isomer levamisole, tetramisole is the classic representative of the imidazothiazole chemical class.
Step 3: Final Answer:
Therefore, Tetramisole is the compound belonging to the Imidazothiazole group, making (D) the correct option.
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