Question:
Which of the following anaesthetic drugs is contraindicated in a patient with hypertension who is being posted for cholecystectomy?
Which of the following anaesthetic drugs is contraindicated in a patient with hypertension who is being posted for cholecystectomy?
Show Hint
Which induction agent raises BP and heart rate via sympathetic stimulation?
Updated On: Jun 24, 2026
- Ketamine
- Propofol
- Etomidate
- Midazolam
Show Solution
Verified By Collegedunia
The Correct Option is A
Solution and Explanation
Step 1: Identify the haemodynamic profile required: in a hypertensive patient we must avoid an agent that further raises blood pressure and heart rate.
Step 2: Ketamine is a dissociative anaesthetic that stimulates the sympathetic nervous system and inhibits noradrenaline re-uptake. This produces a rise in heart rate, blood pressure, cardiac output, and myocardial oxygen demand.
Step 3: These sympathomimetic effects make ketamine relatively contraindicated in uncontrolled or poorly controlled hypertension, as well as in ischaemic heart disease and raised intracranial pressure.
Step 4: Comparing the alternatives: Propofol tends to lower blood pressure; Etomidate is notably cardiostable; Midazolam causes only mild cardiovascular depression. All three are far safer than ketamine in a hypertensive patient.
Conclusion: Ketamine is the contraindicated agent (option 1), matching the printed key.
Step 2: Ketamine is a dissociative anaesthetic that stimulates the sympathetic nervous system and inhibits noradrenaline re-uptake. This produces a rise in heart rate, blood pressure, cardiac output, and myocardial oxygen demand.
Step 3: These sympathomimetic effects make ketamine relatively contraindicated in uncontrolled or poorly controlled hypertension, as well as in ischaemic heart disease and raised intracranial pressure.
Step 4: Comparing the alternatives: Propofol tends to lower blood pressure; Etomidate is notably cardiostable; Midazolam causes only mild cardiovascular depression. All three are far safer than ketamine in a hypertensive patient.
Conclusion: Ketamine is the contraindicated agent (option 1), matching the printed key.
Was this answer helpful?
0
0
Top NEET PG Anaesthesia Questions
- Identify the maneuver being performed in the given image.
- Which of the following is the drug of choice for preoperative antibiotic prophylaxis in a patientundergoing cardiac surgery?
- During resuscitation, when is the given position indicated :
- During squint surgery, anesthesiologist sees the machine and see the bp suddenly drops to 40. What will be best immediate management ?
- A critically ill patient with COVID-19 is admitted to the ICU and is currently on mechanical ventilation. The \(PaO_2/FiO_2\) ratio is 100, indicating severe ARDS. Which of the following is the most appropriate ventilatory strategy?
View More Questions
Top NEET PG Intravenous induction agents Questions
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions