Step 1: Concept
Bacteria have evolved complex immune defense mechanisms to protect themselves against foreign genetic invaders, particularly bacteriophages (viruses that infect bacteria).
Step 2: Restriction-Modification (R-M) System
The primary defense mechanism is the Restriction-Modification system, which consists of two key enzymes:
1. Restriction Endonucleases: These enzymes recognize specific, short palindromic sequences in foreign DNA and cut both strands, rendering the invading viral DNA non-functional.
2. Methyltransferases: These enzymes methylate specific bases (adenine or cytosine) within the host bacterium's own restriction sites. This methylation sterically prevents host endonucleases from binding, protecting the bacterium's own DNA from self-destruction.
Step 3: Conclusion
Hence, the natural restriction defense mechanism is intended for the selective destruction of invading viral (bacteriophage) DNA, matching option (C).
Final Answer: (C)