Question

Name the disorder caused by trisomy of sex chromosomes

• A. Klinefelter’s syndrome
• B. Edward’s syndrome
• C. Down’s syndrome
• D. Turner’s syndrome

Hint:

Klinefelter = XXY (sex chromosome trisomy).

Answer 1

The Correct Option is A

Step 1: Understanding chromosomal disorders.
Chromosomal disorders occur due to abnormal number of chromosomes. Trisomy refers to the presence of an extra chromosome, leading to genetic imbalance and developmental issues.

Step 2: Sex chromosome abnormalities.
Sex chromosome trisomy typically involves an extra X chromosome in males, resulting in XXY configuration. This condition affects physical and reproductive development.

Step 3: Klinefelter’s syndrome.
Klinefelter’s syndrome occurs in males with an extra X chromosome (47, XXY). It is a classic example of sex chromosome trisomy and leads to infertility and other physiological changes.

Step 4: Analysis of other options.
Down’s syndrome is trisomy 21, Edward’s syndrome is trisomy 18, and Turner’s syndrome involves monosomy X (45, X). Hence they are incorrect.

Step 5: Genetic impact.
The extra X chromosome in Klinefelter’s syndrome leads to hormonal imbalance and underdeveloped secondary sexual characteristics.

Step 6: Final conclusion.
Thus, the correct answer is Klinefelter’s syndrome.