Question:
All of the following factors contribute to resurgence of malaria, except:
All of the following factors contribute to resurgence of malaria, except:
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Drugs act on the parasite, not the host, so host drug resistance is meaningless.
Updated On: Jun 24, 2026
- Drug resistance in host
- Drug resistance in parasite
- Drug resistance in vectors
- Antigenic variations in parasite
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The Correct Option is A
Solution and Explanation
Step 1: Understand malaria resurgence.
Resurgence means a return or rise of malaria after earlier control. It results from technical, administrative, financial and operational failures, plus biological resistance factors in the parasite and the mosquito vector.
Step 2: Evaluate each option.
Drug resistance in the parasite (for example chloroquine resistant Plasmodium falciparum) is a real and major cause of resurgence. Valid.
Resistance in vectors, strictly meaning insecticide resistance in the Anopheles mosquito, lets the vector survive control measures and is a recognised contributor. Valid.
Antigenic variation in the parasite helps it evade immunity and sustain transmission, contributing to persistence and resurgence. Valid.
Step 3: Identify the exception.
"Drug resistance in host" is not a meaningful concept. The human host does not develop resistance to antimalarial drugs; resistance is a property of the parasite, and insecticide resistance is a property of the vector. So this option is the odd one out.
Answer: Option A.
Resurgence means a return or rise of malaria after earlier control. It results from technical, administrative, financial and operational failures, plus biological resistance factors in the parasite and the mosquito vector.
Step 2: Evaluate each option.
Drug resistance in the parasite (for example chloroquine resistant Plasmodium falciparum) is a real and major cause of resurgence. Valid.
Resistance in vectors, strictly meaning insecticide resistance in the Anopheles mosquito, lets the vector survive control measures and is a recognised contributor. Valid.
Antigenic variation in the parasite helps it evade immunity and sustain transmission, contributing to persistence and resurgence. Valid.
Step 3: Identify the exception.
"Drug resistance in host" is not a meaningful concept. The human host does not develop resistance to antimalarial drugs; resistance is a property of the parasite, and insecticide resistance is a property of the vector. So this option is the odd one out.
Answer: Option A.
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