Question:

All of the following are markers of acute kidney injury EXCEPT?

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One option is the acid form of an enzyme; the alkaline form is the real renal marker.
Updated On: Jun 24, 2026
  • Clusterin
  • Osteopontin
  • Alanine aminopeptidase
  • Acid phosphatase
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The Correct Option is D

Solution and Explanation

Step 1: Acute kidney injury (AKI) is detected early by a panel of urinary and serum biomarkers that reflect tubular damage and stress. The question asks which listed substance is NOT a recognised AKI marker.

Step 2: Clusterin, osteopontin and alanine aminopeptidase are all established markers of acute kidney injury, along with KIM-1, NGAL, IL-18, cystatin C, NAG and others.

Step 3: Acid phosphatase is not part of the AKI biomarker panel, so the exception is option d, acid phosphatase.

Step 4: Note that alkaline phosphatase (not acid phosphatase) is among the tubular enzyme markers, which is the likely source of the distractor.
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